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Children's Oncology Group Selected Research

Ice

2/2009A study of rituximab and ifosfamide, carboplatin, and etoposide chemotherapy in children with recurrent/refractory B-cell (CD20+) non-Hodgkin lymphoma and mature B-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group.
4/2005A phase I clinical, pharmacologic, and biologic study of thrombopoietin and granulocyte colony-stimulating factor in children receiving ifosfamide, carboplatin, and etoposide chemotherapy for recurrent or refractory solid tumors: a Children's Oncology Group experience.

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Children's Oncology Group Research Topics

Disease

38Neoplasms (Cancer)
06/2023 - 01/2002
15Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
02/2009 - 07/2004
7Leukemia
04/2008 - 01/2002
6Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
02/2013 - 02/2006
6Ewing Sarcoma (Sarcoma, Ewing)
03/2009 - 01/2006
5Infections
06/2023 - 01/2002
5Neuroblastoma
09/2010 - 03/2006
4Glioma (Gliomas)
12/2010 - 11/2006
4Sarcoma (Soft Tissue Sarcoma)
10/2009 - 08/2006
4Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
04/2008 - 03/2003
4Hodgkin Disease (Hodgkin's Disease)
06/2006 - 01/2002
3Sepsis (Septicemia)
06/2023 - 01/2002
3Hypersensitivity (Allergy)
09/2010 - 01/2002
3Osteosarcoma (Osteogenic Sarcoma)
11/2009 - 05/2007
3Thrombocytopenia (Thrombopenia)
03/2009 - 04/2005
3Neutropenia
03/2009 - 01/2002
3Rhabdomyosarcoma
03/2008 - 08/2006
3Primitive Neuroectodermal Tumors (PNET)
12/2007 - 01/2006
2Non-Hodgkin Lymphoma (Lymphosarcoma)
06/2023 - 02/2009
2Osteonecrosis (Kienbock's Disease)
09/2012 - 05/2008
2Hypocalcemia
12/2009 - 08/2006
2Breast Neoplasms (Breast Cancer)
12/2008 - 01/2002
2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
10/2008 - 09/2007
2Thrombosis (Thrombus)
05/2008 - 07/2004
2Typhlitis
04/2008 - 01/2002
2Medulloblastoma
03/2008 - 12/2007
2Hypotension (Low Blood Pressure)
03/2006 - 01/2002
1Poliomyelitis (Polio)
06/2023
1Agammaglobulinemia (Hypogammaglobulinemia)
06/2023
1Lymphopenia (Lymphocytopenia)
06/2023
1Brain Neoplasms (Brain Tumor)
07/2015
1Myeloid Leukemia (Leukemia, Myelocytic)
02/2013
1Residual Neoplasm
12/2012
1Ependymoma
12/2012
1Turcot syndrome
12/2010
1Pain (Aches)
09/2010
1Capillary Leak Syndrome
09/2010
1Hepatoblastoma
12/2009
1Hearing Loss (Hearing Impairment)
12/2009
1Wilms Tumor (Wilm's Tumor)
12/2008
1Stomatitis
10/2008
1Hypertension (High Blood Pressure)
10/2008
1Central Nervous System Diseases (CNS Diseases)
10/2008

Drug/Important Bio-Agent (IBA)

6Etoposide (VP 16)FDA LinkGeneric
02/2009 - 01/2002
5Doxorubicin (Adriamycin)FDA LinkGeneric
02/2008 - 01/2002
5Vincristine (Oncovin)FDA LinkGeneric
02/2007 - 01/2002
4Cisplatin (Platino)FDA LinkGeneric
12/2012 - 03/2003
4Monoclonal AntibodiesIBA
09/2010 - 03/2006
4Proteins (Proteins, Gene)FDA Link
03/2009 - 09/2006
4IfosfamideFDA LinkGeneric
02/2009 - 04/2005
4Bleomycin (Blenoxane)FDA LinkGeneric
06/2006 - 01/2002
3Rituximab (Mabthera)FDA Link
06/2023 - 09/2007
3Carboplatin (JM8)FDA LinkGeneric
07/2015 - 04/2005
3ParaffinIBA
12/2008 - 05/2007
3Transaminases (Aminotransferases)IBA
10/2008 - 01/2002
2Alkylating AgentsIBA
12/2010 - 01/2002
2Interleukin-2 (IL2)IBA
09/2010 - 03/2006
2Isotretinoin (Accutane)FDA LinkGeneric
09/2010 - 01/2009
2Amifostine (Ethyol)FDA LinkGeneric
12/2009 - 08/2005
2Cytarabine (Cytosar-U)FDA LinkGeneric
03/2009 - 08/2006
2IceIBA
02/2009 - 04/2005
2Docetaxel (Taxotere)FDA Link
03/2008 - 04/2006
2Methotrexate (Mexate)FDA LinkGeneric
02/2008 - 08/2006
2Gefitinib (Iressa)FDA Link
09/2007 - 09/2005
2Biomarkers (Surrogate Marker)IBA
09/2007 - 11/2005
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
08/2006 - 01/2002
2Prednisone (Sone)FDA LinkGeneric
06/2006 - 01/2002
2Procarbazine (Matulane)FDA Link
06/2006 - 01/2002
1VaccinesIBA
06/2023
1Thiotepa (Triethylenethiophosphoramide)FDA LinkGeneric
07/2015
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
02/2013
1LigandsIBA
02/2013
1Dexamethasone (Maxidex)FDA LinkGeneric
09/2012
1Temozolomide (Temodar)FDA LinkGeneric
12/2010
1dinutuximabIBA
09/2010
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
09/2010
1PlatinumIBA
12/2009
1mifamurtideIBA
11/2009
1Vinorelbine (Navelbine)FDA LinkGeneric
10/2009
1AlkaloidsIBA
10/2009
1Formaldehyde (Formol)FDA Link
12/2008
1Fixatives (Pickling Agents)IBA
12/2008
1Phosphates (Orthophosphate)IBA
12/2008
1BuffersIBA
12/2008
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
10/2008
1motexafin gadoliniumIBA
10/2008
1Gemtuzumab (Mylotarg)FDA Link
05/2008
1GlucocorticoidsIBA
05/2008

Therapy/Procedure

28Therapeutics
06/2023 - 01/2002
21Drug Therapy (Chemotherapy)
06/2023 - 01/2002
3Radiotherapy
10/2008 - 01/2002
2Stem Cell Transplantation
09/2010 - 12/2008
2Chemoradiotherapy
01/2009 - 06/2006
2Transplantation
02/2008 - 06/2006
1Immunotherapy
09/2010
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
12/2008
1Induced Labor
12/2008
1Induction Chemotherapy
12/2008
1Aftercare (After-Treatment)
10/2008
1Maintenance Chemotherapy
10/2008